The groundwater source heat pump system is one of the main ways of shallow geothermal resources development. This paper gives an introduction to HST3D code, which is widely used in China to simulate heat mobilization, and analyzes its advantages and disadvantages. Meanwhile, this paper discusses the application of HST3D code in heat mobilization simulation based on case study on underground water source pump engineering at Zhengzhou Children Hospital. This simulation analyzes the temperature changes in two wells in 8 years, of which the temperature increases no more than 1 Celsius degrees at No.3 well where is near the injection wells, and no more than 0.5 Celsius degree at No.6 well where is relatively far from the injection wells, consistent with real water temperature changes.